The NANoREG project: 'A common European approach to the regulatory testing of nanomaterials', funded by the European Union's 7th Framework Programme, under grant agreement nr. 310584 (http://cordis.europa.eu/project/rcn/107159_en.html) produced two major project outputs: the NANoREG Framework and the NANoREG Toolbox for the Safety Assessment of Nanomaterials. The Toolbox supports the implementation of the Framework by providing an overview of available tools (test methods, datasets, models, guidance documents, decision trees, etc.) useful to regulators and other stakeholders in the European REACH context. In this dataset, these tools and the purpose, type, regulatory acceptability status and access information of as well as other metadata about each tool are recorded. The two separate files of the dataset cover presently available (Toolbox) and upcoming tools (Prospective tools).